|
rs1048943
|
|
Gallbladder Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.
|
18990008 |
2009 |
|
rs1048943
|
|
Stage IV Gallbladder Cancer AJCC v8
|
|
0.030 |
GeneticVariation
|
BEFREE |
We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.
|
18990008 |
2009 |
|
rs1048943
|
|
Stage IIB Gallbladder Cancer AJCC v8
|
|
0.030 |
GeneticVariation
|
BEFREE |
We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.
|
18990008 |
2009 |
|
rs1048943
|
|
Malignant neoplasm of gallbladder
|
|
0.030 |
GeneticVariation
|
BEFREE |
We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.
|
18990008 |
2009 |
|
rs1048943
|
|
Stage 0 Gallbladder Cancer AJCC v8
|
|
0.030 |
GeneticVariation
|
BEFREE |
We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.
|
18990008 |
2009 |
|
rs1048943
|
|
Stage III Gallbladder Cancer AJCC v8
|
|
0.030 |
GeneticVariation
|
BEFREE |
We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.
|
18990008 |
2009 |
|
rs1048943
|
|
Stage IIA Gallbladder Cancer AJCC v8
|
|
0.030 |
GeneticVariation
|
BEFREE |
We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.
|
18990008 |
2009 |
|
rs1048943
|
|
Malignant neoplasm of breast
|
|
0.080 |
GeneticVariation
|
BEFREE |
We investigated the associations between two CYP1A1 polymorphisms (Ile462Val and Thr461Asn) and one CYP1B1 polymorphism (Leu432Val) and breast cancer risk.
|
17063266 |
2007 |
|
rs1048943
|
|
Breast Carcinoma
|
|
0.080 |
GeneticVariation
|
BEFREE |
We investigated the associations between two CYP1A1 polymorphisms (Ile462Val and Thr461Asn) and one CYP1B1 polymorphism (Leu432Val) and breast cancer risk.
|
17063266 |
2007 |
|
rs1048943
|
|
Breast Carcinoma
|
|
0.080 |
GeneticVariation
|
BEFREE |
We here carried out a population based case-control study of the CYP MspI (CYP1A1*1/M1) and Ile462Val (CYP1A1*2/M2) polymorphisms in CYP1A1 to clarify their importance in determining breast cancer susceptibility in a South Indian population.
|
22292665 |
2011 |
|
rs1048943
|
|
Malignant neoplasm of breast
|
|
0.080 |
GeneticVariation
|
BEFREE |
We here carried out a population based case-control study of the CYP MspI (CYP1A1*1/M1) and Ile462Val (CYP1A1*2/M2) polymorphisms in CYP1A1 to clarify their importance in determining breast cancer susceptibility in a South Indian population.
|
22292665 |
2011 |
|
rs1048943
|
|
Malignant neoplasm of breast
|
|
0.080 |
GeneticVariation
|
BEFREE |
We examined the potential association of breast cancer risk in Mexican women with the polymorphisms CYP1A1 rs1048943, CYP1B1 rs1056836, COMT rs4680, GSTP1 rs1695, GSTT1 null and GSTM1 null which are involved in estrogen metabolism pathway.
|
23000097 |
2013 |
|
rs1048943
|
|
Breast Carcinoma
|
|
0.080 |
GeneticVariation
|
BEFREE |
We examined the potential association of breast cancer risk in Mexican women with the polymorphisms CYP1A1 rs1048943, CYP1B1 rs1056836, COMT rs4680, GSTP1 rs1695, GSTT1 null and GSTM1 null which are involved in estrogen metabolism pathway.
|
23000097 |
2013 |
|
rs1048943
|
|
Stomach Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
We examined the association between single nucleotide polymorphisms (SNPs) of CYP1A1 (rs4646421, rs4646422 and rs1048943), GSTM1 and GSTT1 and gastric cancer risk in Japan.
|
27062139 |
2016 |
|
rs1048943
|
|
Malignant neoplasm of stomach
|
|
0.030 |
GeneticVariation
|
BEFREE |
We examined the association between single nucleotide polymorphisms (SNPs) of CYP1A1 (rs4646421, rs4646422 and rs1048943), GSTM1 and GSTT1 and gastric cancer risk in Japan.
|
27062139 |
2016 |
|
rs1048943
|
|
Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
We evaluated potential associations between smoking and polymorphisms in PAH metabolism [CYP1A1 Ile 462Val, CYP1B1 Ala 119Ser and Leu 432Val, microsomal epoxide hydrolase (mEH) Tyr 113His and His139Arg, CYP3A4 A(-392)G] and conjugation [glutathione S-transferase (GST) M1 null deletion, GSTP1 Ile 105Val] genes and PAH-DNA adduct levels (measured by immunohistochemistry) in tumor and nontumor prostate cells in 400 prostate cancer cases.
|
17548691 |
2007 |
|
rs1048943
|
|
Malignant neoplasm of endometrium
|
|
0.030 |
GeneticVariation
|
BEFREE |
We did not observe any statistically significant associations between the MspI, Thr461Asn or Ile462Val polymorphisms and endometrial cancer risk or any significant effect modification by cigarette-smoking status.
|
17717632 |
2007 |
|
rs1048943
|
|
Endometrial Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
We did not observe any statistically significant associations between the MspI, Thr461Asn or Ile462Val polymorphisms and endometrial cancer risk or any significant effect modification by cigarette-smoking status.
|
17717632 |
2007 |
|
rs1048943
|
|
Uterine Fibroids
|
|
0.040 |
GeneticVariation
|
BEFREE |
We concluded that the carriage of CYP1A1 Ile462Val AG and CYP1B1 Leu 432Val CC genotypes predict the susceptibility to leiomyoma in Egyptian women and they are likely to contribute in the pathogenesis of leiomyoma.
|
20559649 |
2011 |
|
rs1048943
|
|
Fibroid Tumor
|
|
0.010 |
GeneticVariation
|
BEFREE |
We concluded that the carriage of CYP1A1 Ile462Val AG and CYP1B1 Leu 432Val CC genotypes predict the susceptibility to leiomyoma in Egyptian women and they are likely to contribute in the pathogenesis of leiomyoma.
|
20559649 |
2011 |
|
rs1048943
|
|
Malignant Neoplasms
|
|
0.060 |
GeneticVariation
|
BEFREE |
Variant alleles found to increase the risk of developing TCa were CYP1A1*2C (rs1048943), GSTP1 (rs1695), and GSTT1null, especially when in conjunction with a cancer family history and/or a smoking habit.
|
31107374 |
2019 |
|
rs1048943
|
|
Primary malignant neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
Variant alleles found to increase the risk of developing TCa were CYP1A1*2C (rs1048943), GSTP1 (rs1695), and GSTT1null, especially when in conjunction with a cancer family history and/or a smoking habit.
|
31107374 |
2019 |
|
rs1048943
|
|
Malignant neoplasm of testis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Variant alleles found to increase the risk of developing TCa were CYP1A1*2C (rs1048943), GSTP1 (rs1695), and GSTT1null, especially when in conjunction with a cancer family history and/or a smoking habit.
|
31107374 |
2019 |
|
rs1048943
|
|
Malignant Testicular Germ Cell Tumor
|
|
0.010 |
GeneticVariation
|
BEFREE |
Variant alleles found to increase the risk of developing TCa were CYP1A1*2C (rs1048943), GSTP1 (rs1695), and GSTT1null, especially when in conjunction with a cancer family history and/or a smoking habit.
|
31107374 |
2019 |
|
rs1048943
|
|
Malignant neoplasm of prostate
|
|
0.050 |
GeneticVariation
|
BEFREE |
To investigate this, we studied the association between prostate cancer and smoking, as well as the main and modifying effects of functional polymorphisms in genes that metabolize polycyclic aromatic hydrocarbons (CYP1A1 Ile(462)Val, microsomal epoxide hydrolase His(139)Arg) and detoxify reactive derivatives (GSTM1 null deletion, GSTT1 null deletion, GSTP1 Ile(105)Val and Ala(114)Val) using a family-based case-control design (439 prostate cancer cases and 479 brother controls).
|
16614120 |
2006 |